Colorectal cancer is the 4th leading cause of cancer mortality.
This study aimed to can multidetector CT scan (MDCT) replace Magnetic resonance imaging (MRI) for mesorectal fasca in rectal cancer?
This cross-sectional was conducted on patients with rectal cancer in Alzahra and Seyed-Shohada hospitals. MRI, mesorectal fascia (MPR), and axial MDCT were provided from patients to assess the involvement of mesorectal fascia. Sensitivity, specificity, positive and negative predictive values were assessed in these patients. Kappa coefficient agreement was used for analysis. Patients were also divided into different subgroups based on gender, tumoral location, nodal involvement, and tumoral description as mass or wall thickening to evaluate the accuracy of MDCT for assessing mesorectal fascia involvement.
The current study was conducted on 60 patients with rectal cancer. Regarding MRF involvement, the frequency of patients who were correctly diagnosed by MPR and axial MDCT was 45 (75%) and 35 (58.3%), respectively. There was no agreement between axial MDCT and MRI regarding MRF involvement (P>0.05), however, an agreement was seen between Multiplanar reconstruction CT (MPRCT) and MRI method regarding MRF involvement (Pkappa=0.44). Moreover MPRCT scan has a more acceptable agreement with MRI in patients with wall thickening (comparing with patients described as having mass lesion) (Kappa= 0.699, P=0.001) and negative nodal involvement. Also, there was more agreement between MPRCT scan and MRI in tumors located in the middle or upper rectum compared with the lower rectum.
According to these findings, there was good agreement between MRI and MPRCT regarding MRF involvement at patients with wall thickening and negative nodal involvement in the upper and middle rectum; it seems that MPRCT method which is now used for routine staging can be comparable with MRI for some subgroups of patients for evaluating MRF and can replace it in these patients.
Farghdani, Maryam; Karami, Mehdi; and Fallah, Amirafraz
"Can multidetector CT scan replace MRI for evaluation of mesorectal fasca in rectal cancer?,"
BioMedicine: Vol. 13
, Article 8.
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