Abstract
Background: Osteoarthritis is a syndrome characterized by joint pain and reduced performance and efficien- cy in patient.Thymus daenensishas been used since old times for the treatment of bone and joint deformities and pain in traditional medicine.
Purpose: This study was conducted to examine traditional usages and pharmacological features ofT. daen- ensiswith respect to the effect of the plant in patients with osteoarthritis.
Methods: 120 patients with osteoarthritis were divided into 3 groups. Patients in each group were treated by 5%Thymus daenensisgel, 1% diclofenac gel, or placebo for 6 weeks, along with oral celecoxib capsules. Patients were assessed in different intervals, based on the VAS score for assessment of pain in the joint and different dimensions of WOMAC questionnaire.
Results: Pain level (P< 0.005), stiffness during the day (P< 0.05), morning stiffness (P< 0.05) and physi- cal performance (P< 0.05) were significantly different among the groups.
Conclusions:Thymus daenensisgel improves the symptoms in patients equal and without significant difference than diclofenac group. It can be argued that its use can produce a satisfactory effect on patients with osteoarthritis due to its low cost, easy access, the plant’s natively occurring in Iran.
Recommended Citation
Dehghan, Morteza; Asgharian, Shirin; Khalesi, Elena; Ahmadi, Ali; and Lorigooini, Zahra
(2024)
"Comparative study of the effect of Thymus daenensis gel 5% and diclofenac in patients with knee osteoarthritis,"
BioMedicine: Vol. 9
:
Iss.
2
, Article 2.
DOI: 10.37796/2211-8039.1611
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This work is licensed under a Creative Commons Attribution 4.0 License.
